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Human Chromogranin A Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB90982

R&D Systems, part of Bio-Techne
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MAB90982-100
MAB90982-SP

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 948130

Product Summary for Human Chromogranin A Antibody

Immunogen

Human embryonic kidney cell line HEK293-derived human Chromogranin A
Met1-Gly457
Accession # P10645

Specificity

Detects human Chromogranin A in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human Chromogranin A Antibody

Human Chromogranin A ELISA Standard Curve.

Recombinant Human Chromogranin A protein was serially diluted 2-fold and captured by Mouse Anti-Human Chromogranin A Monoclonal Antibody (Catalog # MAB9098) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human Chromogranin A Monoclonal Antibody (Catalog # MAB90982) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994).

Applications for Human Chromogranin A Antibody

Application
Recommended Usage

ELISA

This antibody functions as an ELISA detection antibody when paired with Mouse Anti-Human Chromogranin A Monoclonal Antibody (Catalog # MAB9098).

This product is intended for assay development on various assay platforms requiring antibody pairs. We recommend the Human Chromogranin A DuoSet ELISA Kit (Catalog # DY9098-05) for convenient development of a sandwich ELISA.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Chromogranin A

Human Chromogranin A (CHGA) an acidic protein and a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in pancreas. Chromogranin A expression has been oberserved in neuroendocrine tumors, medullary thyroid carcinoma, as well as carcinoid tumors.

Alternate Names

Betagranin, Catestatin, CHGA, Chromofungin, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I

Entrez Gene IDs

1113 (Human); 12652 (Mouse); 24258 (Rat)

Gene Symbol

CHGA

UniProt

Additional Chromogranin A Products

Product Documents for Human Chromogranin A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Chromogranin A Antibody

For research use only

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