Human CLEC4D/CLECSF8 APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB2806A
Clone 413512 was used by HLDA to establish CD designation
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2B Clone # 413512
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CLEC4D/CLECSF8
Gly52-Asn215
Accession # Q8WXI8
Gly52-Asn215
Accession # Q8WXI8
Specificity
Detects human CLEC4D/CLECSF8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CLECSF9, rhCLECSF13, rhOCIL, or rhOCILrp2 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Human CLEC4D/CLECSF8 APC-conjugated Antibody
Detection of CLEC4D/CLECSF8 in Whole Blood Monocytes by Flow Cytometry.
Whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 APC-conjugated Monoclonal Antibody (Catalog # FAB2806A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human CLEC4D/CLECSF8 APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Whole blood monocytes
Sample: Whole blood monocytes
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: CLEC4D/CLECSF8
CLEC4D (C-type lectin domain family 4 member D), also known as CLCSF8, CLEC-6, and MCL, is a 30 kDa type II transmembrane (TM) glycoprotein that belongs to the CLR (C-type Lectin Receptor) family of molecules. It is synthesized as a 215 amino acid (aa) protein that contains a 17 aa N-terminal cytoplasmic domain, a 21 aa TM segment, and a 177 aa C-terminal extracellular region. The extracellular region shows a short stalk and a 118 aa CRD (carbohydrate recognition domain). The nature of its carbohydrate ligand is unknown. CLEC4D is restricted to monocytes/macrophages and serves as an endocytic receptor. Homodimers and homotrimers form on the cell surface. The human CLEC4D extracellular region shares 63% aa sequence identity with the mouse extracellular region.
Long Name
C-type Lectin Domain Family 4, Member D
Alternate Names
CD368, CLEC6, CLECSF8, Mpcl
Gene Symbol
CLEC4D
UniProt
Additional CLEC4D/CLECSF8 Products
Product Documents for Human CLEC4D/CLECSF8 APC-conjugated Antibody
Product Specific Notices for Human CLEC4D/CLECSF8 APC-conjugated Antibody
For research use only
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