Human CMG-2/ANTXR2 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB29401
Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 406510
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CMG-2/ANTXR2
Ser22-Arg200
Accession # P58335
Ser22-Arg200
Accession # P58335
Specificity
Detects human CMG-2/ANTXR2 in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human CMG-2/ANTXR2 Antibody
Application
Recommended Usage
ELISA
This antibody functions as an ELISA capture antibody when paired with Goat Anti-Human CMG‑2/ANTXR2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2940).
This product is intended for assay development on various assay platforms requiring antibody pairs.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CMG-2/ANTXR2
Capillary Morphogenesis Protein 2 (CMG-2) is an anthrax toxin receptor (ATR) family protein that contains a von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus Anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment of anthrax. Within the region used as immunogen, human and mouse CMG-2 share 76% amino acid sequence homology.
Long Name
Capillary Morphogenesis Protein 2
Alternate Names
ANTXR2, cI-35, CMG2, ISH, JHS
Gene Symbol
ANTXR2
UniProt
Additional CMG-2/ANTXR2 Products
Product Documents for Human CMG-2/ANTXR2 Antibody
Product Specific Notices for Human CMG-2/ANTXR2 Antibody
For research use only
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