Human CX3CR1 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB5204P

R&D Systems, part of Bio-Techne
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FAB5204P-100
FAB5204P-025
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 528728

View all CX3CR1 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human CX3CR1
Met1-Thr31, Leu91-Lys103, Thr168-Thr195, Lys257-Leu273
Accession # NP_001328

Specificity

Detects human CX3CR1 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human CX3CR1 PE-conjugated Antibody

Detection of CX3CR1 antibody in Human Blood Monocytes antibody by Flow Cytometry.

Detection of CX3CR1 in Human Blood Monocytes by Flow Cytometry.

Human peripheral blood monocytes were stained with Mouse Anti-Human CX3CR1 PE-conjugated Monoclonal Antibody (Catalog # FAB5204P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Detection of CX3CR1 antibody in Human PBMC antibody by Flow Cytometry.

Detection of CX3CR1 in Human PBMC by Flow Cytometry.

Human PBMC were stained with (A) Mouse Anti-Human CX3CR1 PE-conjugated Monoclonal Antibody (Catalog # FAB5204P) or (B) Mouse IgG1 isotype control antibody (Catalog # IC002P) and Mouse anti-Human CD14 APC-conjugated antibody (Catalog # FAB3832A). Staining was done at 37oC. View our protocol for Staining Membrane-associated Proteins.

Applications for Human CX3CR1 PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human peripheral blood monocytes

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CX3CR1

CX3CR1 is a 40 kDa seven transmembrane chemokine receptor that is expressed on several T cell subsets, monocytes, macrophages, microglia, and epithelial cells. CX3CR1 binding to membrane bound or soluble CX3CR1/Fractalkine promotes inflammatory responses by inducing monocyte adhesion to endothelial cells and macrophage activation. CX3CR1 polymorphisms are associated with the development of chronic inflammatory disorders. Alternately spliced isoforms have extended N-terminal extracellular regions that increase the potency of CX3CR1 as a fusion co-receptor for HIV-1. Human CX3CR1 shares 82% amino acid sequence identity with mouse and rat CX3CR1.

Long Name

CX3C Chemokine Receptor 1

Alternate Names

CMKbRL1, V28

Entrez Gene IDs

1524 (Human); 13051 (Mouse); 171056 (Rat)

Gene Symbol

CX3CR1

UniProt

NP_001328

Additional CX3CR1 Products

Product Documents for Human CX3CR1 PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human CX3CR1 PE-conjugated Antibody

For research use only

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