Human DLL3 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB4315
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 378703
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human DLL3
Ala27-Pro488
Accession # Q9NYJ7
Ala27-Pro488
Accession # Q9NYJ7
Specificity
Detects human DLL3 in direct ELISAs and Western blots. Does not cross‑react with recombinant human (rh) DLL1 or rhDLL4.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human DLL3 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human DLL3
Sample: Recombinant Human DLL3
Reviewed Applications
Read 8 reviews rated 4.3 using MAB4315 in the following applications:
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: DLL3
Delta-like 3 (DLL3) is a transmembrane Delta-like protein that contains one DSL domain and six EGF-like repeats. DLL3 is critical for somite segmentation and neurogenesis during early embryonic development. It does not bind Notch receptors but functions as an antagonist of Notch signaling. Defects in DLL3 cause axial skeletal abnormalities in spondylocostal dysostosis. Within the extracellular domain, human DLL3 shares 84% amino acid sequence identity with mouse and rat DLL3.
Long Name
Delta-like 3
Alternate Names
Pudgy, SCDO1
Gene Symbol
DLL3
UniProt
Additional DLL3 Products
Product Documents for Human DLL3 Antibody
Product Specific Notices for Human DLL3 Antibody
For research use only
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