Human EphA10 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB5188
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 494130
Product Specifications
Immunogen
E. coli-derived recombinant human EphA10
Glu34-Glu283 (predicted)
Accession # Q5JZY3
Glu34-Glu283 (predicted)
Accession # Q5JZY3
Specificity
Detects human EphA10 in direct ELISAs. In direct ELISAs, no
cross-reactivity with recombinant human EphA1, A2, A5, A6, B2, B3, B4, B6,
recombinant mouse EphA3, A4, or A8 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human EphA10 Antibody
Application
Recommended Usage
Immunohistochemistry
8-25 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human brain (cortex)
Sample: Immersion fixed paraffin-embedded sections of human brain (cortex)
Reviewed Applications
Read 2 reviews rated 5 using MAB5188 in the following applications:
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Sterile PBS to a final concentration of 0.5 mg/mL. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: EphA10
EphA10 is a member of the Eph family of receptor tyrosine kinases that are activated by binding members of the Ephrin ligand family. EphA10 preferentially binds Ephrin-A3, -A4 and -A5. EphA10 mRNA expression appears limited to the testis, unlike most Ephs that are expressed in developing and adult neural tissue. Human EphA10 extracellular domain (ECD) shares 95% and 88% amino acid identity with mouse and rat EphA10, respectively. Of three alternately spliced isoforms, one is truncated within the ECD and another within the cytoplasmic domain.
Long Name
Eph Receptor A10
Alternate Names
EC 2.7.10.1, EPH receptor A10, EphA10s protein, ephrin type-A receptor 10, FLJ16103, FLJ33655, MGC43817
Gene Symbol
EPHA10
UniProt
Additional EphA10 Products
Product Documents for Human EphA10 Antibody
Product Specific Notices for Human EphA10 Antibody
For research use only
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