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Human FCRL4/FcRH4 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF2426

R&D Systems, part of Bio-Techne
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BAF2426

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Western Blot

Cited:

Immunocytochemistry

Label

Biotin

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4
Gln16-Asp385
Accession # Q96PJ5

Specificity

Detects human FCRL4/FcRH4 in Western blots. In Western blots, less than 2% cross-reactivity with recombinant human (rh) IRTA2, rhIRTA3, rhIRTA4, and rhIRTA5 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human FCRL4/FcRH4 Biotinylated Antibody

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human small intestine (Peyer's patch) and tonsil

Western Blot

0.1 µg/mL
Sample: Recombinant Human FCRL4/FcRH4
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FCRL4/FcRH4

FcRH4, also known as IRTA1 (immunoglobulin superfamily receptor translocation associated 1), is a member of the Ig superfamily. It shares sequence homology with the classical Fc receptors. FcRH4 is preferentially expressed in B cells and contains three potential ITIM motifs in its extracellular domain. The gene for FcRH4 is localized to the human chromosome Iq 21‑23 region, a hotspot for translocation events.

Long Name

Fc Receptor-like protein 4

Alternate Names

CD307d, FcRH4, IGFP2, IRTA1

Entrez Gene IDs

83417 (Human)

Gene Symbol

FCRL4

UniProt

Additional FCRL4/FcRH4 Products

Product Documents for Human FCRL4/FcRH4 Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human FCRL4/FcRH4 Biotinylated Antibody

For research use only

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