Human GFR alpha-4/GDNF R alpha-4 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB1439

R&D Systems, part of Bio-Techne
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MAB1439
MAB1439-SP
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 215725

View all GFR alpha-4/GDNF R alpha-4 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human GFR alpha‑4/GDNF R alpha‑4
Asn24-Ser245 (Ser140Cys)(predicted)
Accession # NP_071422

Specificity

Detects human GFR alpha‑4/GDNF R alpha‑4 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) GFR alpha-1, recombinant rat GFR alpha-1, rhGFR alpha-2, rhGFR alpha-3, or recombinant mouse GFR alpha-4 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human GFR alpha-4/GDNF R alpha-4 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human GFR alpha-4/GDNF R alpha-4

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: GFR alpha-4/GDNF R alpha-4

GFR alpha-4 is a member of a family of at least four cysteine-rich GPI-linked cell surface proteins that function as ligand binding subunits for the GDNF family (GDNF, neurturin, persephin and artemin). A functional receptor complex is achieved through association with the c-Ret receptor tyrosine kinase. GFR alpha-4 preferentially binds persephin.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 4

Alternate Names

GDNF R alpha-4, GFR alpha4, GFRa-4, GFRA4

Entrez Gene IDs

64096 (Human); 14588 (Mouse)

Gene Symbol

GFRA4

UniProt

NP_071422

Additional GFR alpha-4/GDNF R alpha-4 Products

Product Documents for Human GFR alpha-4/GDNF R alpha-4 Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human GFR alpha-4/GDNF R alpha-4 Antibody

For research use only

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