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Human GLP-1R Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB28141

R&D Systems, part of Bio-Techne
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MAB28141
MAB28141-SP

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse, Rat

Applications

Validated:

Immunohistochemistry

Cited:

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 419208

Product Specifications

Immunogen

Baf/3 cell line transfected with human GLP-1R
Accession # P43220

Specificity

Detects human GLP‑1R. Stains human GLP-1R-transfected Baf/3 cells but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human GLP-1R Antibody

GLP-1R antibody in Human Brain by Immunohistochemistry (IHC-P).

GLP‑1R in Human Brain.

GLP-1R was detected in immersion fixed paraffin-embedded sections of human brain (hippocampus) using 3 µg/mL Mouse Anti-Human GLP-1R Monoclonal Antibody (Catalog # MAB28141) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counter-stained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Applications for Human GLP-1R Antibody

Application
Recommended Usage

Immunohistochemistry

8-25 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human brain (hippocampus)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: GLP-1R

Glucagon-Like Peptide-1 Receptor (GLP-1R) is a class B G protein-linked seven transmembrane domain protein that is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. GLP-1R functions as a receptor for glucagon-like peptide 1 and regulates insulin and glucagon production.

Long Name

Glucagon-like Peptide 1 Receptor

Alternate Names

GLP1R

Entrez Gene IDs

2740 (Human); 14652 (Mouse)

Gene Symbol

GLP1R

UniProt

Additional GLP-1R Products

Product Documents for Human GLP-1R Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human GLP-1R Antibody

For research use only

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