Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB11481
Recombinant Monoclonal Antibody For Research Use Only
Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Human IgG1 Clone # Hu209
Product Specifications
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-4 R
Gly24-His232
Accession # P24394
Gly24-His232
Accession # P24394
Specificity
Detects human IL‑4 R alpha in ELISAs.
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Scientific Data Images for Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody
Human IL-4R alpha ELISA Standard Curve
Direct ELISA binding curve demonstrating the recognition of Human Anti-Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Monoclonal Antibody (Catalog # MAB11481) to IL-4R alpha. The target protein was coated onto the microplate well surface, followed by binding of the antibody. A goat anti-human HRP conjugate was used for detection.Applications for Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody
Application
Recommended Usage
ELISA
This
antibody functions as an ELISA detection antibody for the specific antigen in
direct ELISA. Colorimetric detection is performed after addition of a suitable
substrate.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from ascites
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IL-4R alpha
Interleukin 4 receptor (IL-4 R) is the transmembrane ligand binding subunit of the heterodimeric IL-4 receptor complex. In the type I receptor complex, IL-4 R associates with the common gamma chain, whereas in the type II receptor complex, it associates with IL-13 R alpha1. IL-4 R is expressed by B cells, T cells, monocytes and macrophages.
Long Name
Interleukin 4 Receptor alpha
Alternate Names
CD124, IL-4 R alpha, IL-4Ra, IL4R, IL4R alpha
Gene Symbol
IL4R
UniProt
Additional IL-4R alpha Products
Product Documents for Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody
Product Specific Notices for Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody
For research use only
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