Human Marapsin/Pancreasin Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB1988
Key Product Details
Species Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 243305
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Marapsin/Pancreasin
Ala23-Lys290
Accession # Q9BQR3
Ala23-Lys290
Accession # Q9BQR3
Specificity
Detects human Marapsin/Pancreasin in direct ELISAs and Western blots. Reacts with an epitope within the mature chain. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Marapsin is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human Marapsin/Pancreasin Antibody
Application
Recommended Usage
Immunoprecipitation
25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human Marapsin/Pancreasin (Catalog # 1988-SE), see our available Western blot detection antibodies
Sample: Conditioned cell culture medium spiked with Recombinant Human Marapsin/Pancreasin (Catalog # 1988-SE), see our available Western blot detection antibodies
Western Blot
1 µg/mL
Sample: Recombinant Human Marapsin/Pancreasin (Catalog # 1988-SE)
Sample: Recombinant Human Marapsin/Pancreasin (Catalog # 1988-SE)
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Marapsin/Pancreasin
Marapsin, pancreasin, and channel-activating protease 2 (CAP-2) are different names for the same serine protease that is expressed strongly in the pancreas (1, 2). The protein is synthesized with a signal peptide (amino acids 1‑22), a pro peptide (aa 23‑34) and a mature chain (aa 35‑290) corresponding to the serine protease domain.
References
- Bhagwandin, V.J. et al. (2003) J. Biol. Chem. 278:3363.
- Edwards, K.M. et al. (1999) J. Biol. Chem. 274:30468.
Alternate Names
CAP-2, MPN, Pancreasin, PRSS27
Gene Symbol
PRSS27
UniProt
Additional Marapsin/Pancreasin Products
Product Documents for Human Marapsin/Pancreasin Antibody
Product Specific Notices for Human Marapsin/Pancreasin Antibody
For research use only
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