Human Meteorin-like/METRNL Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB7867

Recombinant Monoclonal Antibody
R&D Systems, part of Bio-Techne
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MAB7867-100
MAB7867-SP
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # 781718R

View all Meteorin-like/METRNL Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Meteorin‑like/METRNL
Gln46-Asp311
Accession # Q641Q3

Specificity

Detects human Meteorin‑like/METRNL in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human Meteorin-like/METRNL Antibody

Human Meteorin-like/METRNL Antibody in ELISA Standard Curve.

Human Meteorin‑like/METRNL ELISA Standard Curve.

Recombinant Human Meteorin-like/METRNL protein was serially diluted 2-fold and captured by Mouse Anti-Human Meteorin-like/METRNL Monoclonal Antibody (Catalog # MAB7867) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human Meteorin-like/METRNL Monoclonal Antibody (Catalog # MAB78671) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994).

Applications for Human Meteorin-like/METRNL Antibody

Application
Recommended Usage

ELISA

This antibody functions as an ELISA capture antibody when paired with Mouse Anti-Human Meteorin‑like/METRNL Monoclonal Antibody (Catalog # MAB78671).

This product is intended for assay development on various assay platforms requiring antibody pairs. We recommend the Human Meteorin-like/METRNL DuoSet ELISA Kit (Catalog # DY7867-05) for convenient development of a sandwich ELISA.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Meteorin-like/METRNL

METRNL (Meteorin-like) is a cytoplasmic 30 kDa (predicted) member of the meteorin family of proteins. The name meteorin derives from the ability of the founding family member meteorin to transform glia into cells containing an extensive, meteor-like tail. It is expressed by neurons, and appears to function as a primer molecule that sets the stage for either cell differentiation or neurite outgrowth when it acts with Dclk1 and SerpinB1. Mature human METRNL is 266 amino acids (aa) in length (aa 46-311). It reportedly contains a signal sequence (aa 1-45), which suggests it may be secreted. Mature human and mouse METRNL share 79% aa sequence identity.

Alternate Names

Meteorin like, METRNL

Entrez Gene IDs

284207 (Human); 210029 (Mouse); 316842 (Rat)

Gene Symbol

METRNL

UniProt

Q641Q3

Additional Meteorin-like/METRNL Products

Product Documents for Human Meteorin-like/METRNL Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Meteorin-like/METRNL Antibody

For research use only

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