Skip to main content

Human/Mouse/Rat GDF-11/GDF-8 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB788

R&D Systems, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
Loading...
MAB788-100
MAB788-500
MAB788-SP

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse, Rat, Avian - Chicken, Fish - Paralichthys olivaceus (Olive Flounder or Japanese flatfish)

Applications

Validated:

Western Blot

Cited:

ELISA Development, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2B Clone # 84214

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse GDF-8
Asn25-Ser376
Accession # O08689

Specificity

Detects human, mouse, and rat GDF-8 in direct ELISAs and Western blots. In Western blots, this antibody shows approximately 30% cross-reactivity with recombinant human/mouse/rat GDF-11. In direct ELISAs, this antibody shows less than 1% cross-reactivity with recombinant mouse (rm) GDF-1, rmGDF-3, rmGDF-5, rmGDF-6, and rmGDF-9.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications for Human/Mouse/Rat GDF-11/GDF-8 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human/Mouse/Rat GDF‑8/Myostatin (Catalog # 788-G8)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty
Loading...

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: GDF-11/GDF-8

GDF-8, also known as Myostatin, belongs to the TGF-beta superfamily. It is synthesized as an inactive proprotein with the N-terminal pro-region and the C-terminal mature bioactive region. The GDF-8 proregion is capable of associating with active GDF-8 with high affinity and is a potent GDF-8 antagonist.

Long Name

Growth Differentiation Factor 11/8

Alternate Names

BMP11, BMP-11, bone morphogenetic protein 11, GDF-11, growth/differentiation factor 11, VHO

Entrez Gene IDs

10220 (Human)

Gene Symbol

GDF11

UniProt

Additional GDF-11/GDF-8 Products

Product Documents for Human/Mouse/Rat GDF-11/GDF-8 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human/Mouse/Rat GDF-11/GDF-8 Antibody

For research use only

Loading...
Loading...
Loading...
Loading...