Human NRAMP1/SLC11A1 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB8400A

R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 910825

View all NRAMP1/SLC11A1 Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human NRAMP1/SLC11A1
Met1-Gly550
Accession # NP_000569

Specificity

Detects HEK293 human embryonic kidney cell line transfected with human NRAMP1/SLC11A1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human NRAMP1/SLC11A1 APC-conjugated Antibody

Detection of NRAMP1/SLC11A1 antibody in HEK293 Human Cell Line Transfected with Human NRAMP1/SLC11A1 and eGFP antibody by Flow Cytometry.

Detection of NRAMP1/SLC11A1 in HEK293 Human Cell Line Transfected with Human NRAMP1/SLC11A1 and eGFP by Flow Cytometry.

HEK293 human embryonic kidney cell line transfected with (A) human NRAMP1/SLC11A1 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human NRAMP1/SLC11A1 APC-conjugated Monoclonal Antibody (Catalog # FAB8400A). Quadrant markers were set based on control antibody staining (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins.

Applications for Human NRAMP1/SLC11A1 APC-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: HEK293 human embryonic kidney cell line transfected with human NRAMP1/SLC11A1 and eGFP

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: NRAMP1/SLC11A1

NRAMP1/SLC11A1 (Natural Resistance-Associated Macrophage Protein 1/Solute Carrier family 11, member 1) is a member of the solute carrier family of multi-pass membrane proteins. It functions as a proton-coupled divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in SLC11A1 have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. Alternatively spliced variants that encode different protein isoforms have been described.

Long Name

Natural Resistance-associated Macrophage Protein 1

Alternate Names

LSH, SLC11A1

Entrez Gene IDs

6556 (Human); 18173 (Mouse); 316519 (Rat)

Gene Symbol

SLC11A1

UniProt

NP_000569

Additional NRAMP1/SLC11A1 Products

Product Documents for Human NRAMP1/SLC11A1 APC-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human NRAMP1/SLC11A1 APC-conjugated Antibody

For research use only

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