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Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

R&D Systems, part of Bio-Techne | Catalog # PP-N1404-0C

R&D Systems, part of Bio-Techne
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PP-N1404-0C

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # N1404

Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

Application
Recommended Usage

Immunohistochemistry

Immunoprecipitation

Western Blot

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Nurr1/NGFI-B beta/NR4A2

Nurr1 belongs to the nerve growth factor-induced clone B subfamily of nuclear receptor superfamily and is designated NR4A2 in the Unified Nomenclature System for NRs. Nurr1 can function as a ligand-independent transcription factor. Nurr1 also heterodimerizes with retinoid X receptors (RXRs) to function as ligand-regulated transcription factor. Nurr 1 is important for specification of dopaminergic neurons that degenerate in Parkinsons disease. Human and mouse Nurr1 share 99% amino acid sequence homology.

Long Name

Nur-related Factor 1/Nerve Growth Factor Induced B beta/Nuclear Receptor Subfamily 4, Group A, 2

Alternate Names

NGFI-B beta, NOT, NR4A2, TINUR

Entrez Gene IDs

4929 (Human); 18227 (Mouse)

Gene Symbol

NR4A2

Additional Nurr1/NGFI-B beta/NR4A2 Products

Product Documents for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

For research use only

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