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Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

R&D Systems, part of Bio-Techne | Catalog # PP-N1404-0C

R&D Systems, part of Bio-Techne
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PP-N1404-0C

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # N1404

Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

Application
Recommended Usage

Immunohistochemistry

Immunoprecipitation

Western Blot

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Nurr1/NGFI-B beta/NR4A2

Nurr1 belongs to the nerve growth factor-induced clone B subfamily of nuclear receptor superfamily and is designated NR4A2 in the Unified Nomenclature System for NRs. Nurr1 can function as a ligand-independent transcription factor. Nurr1 also heterodimerizes with retinoid X receptors (RXRs) to function as ligand-regulated transcription factor. Nurr 1 is important for specification of dopaminergic neurons that degenerate in Parkinsons disease. Human and mouse Nurr1 share 99% amino acid sequence homology.

Long Name

Nur-related Factor 1/Nerve Growth Factor Induced B beta/Nuclear Receptor Subfamily 4, Group A, 2

Alternate Names

NGFI-B beta, NOT, NR4A2, TINUR

Entrez Gene IDs

4929 (Human); 18227 (Mouse)

Gene Symbol

NR4A2

Additional Nurr1/NGFI-B beta/NR4A2 Products

Product Documents for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)

For research use only

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