Human PEDFR/PNPLA2 Alexa Fluor® 488-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB5387G
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Val162-Thr332
Accession # Q96AD5
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human PEDFR/PNPLA2 Alexa Fluor® 488-conjugated Antibody
Detection of PEDF R/PNPLA2 in Y‑79 Human Cell Line by Flow Cytometry.
Y-79 human retinoblastoma cell line was stained with Mouse Anti-Human PEDF R/PNPLA2 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB5387G, filled histogram) or isotype control antibody (Catalog # IC0041G, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human PEDFR/PNPLA2 Alexa Fluor® 488-conjugated Antibody
Flow Cytometry
Sample: Y‑79 human retinoblastoma cell line
Formulation, Preparation, and Storage
Purification
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: PEDFR/PNPLA2
PEDF R (Pigment Epithelium-derived Factor Receptor), also known as PNPLA2, ATGL, TTS2.2, iPLA2 zeta (Calcium-independent Phospholipase A2 zeta) and Desnutrin, is a 82-86 kDa type II transmembrane protein that is a member of the patatin-like phospholipase domain-containing protein family (gene name PNPLA2). PEDF is highly expressed in adipose tissue (both white and brown fat cells), where it the catalyzes formation of diacyglycerol from triglyceride, the transfer of an acyl (CoA-fatty acid) derivative to acyl-glycerol, and releases arachidonic acid from intracellular lipid deposits. It has also been found on retinal pigment epithelium, endothelial cells, hepatocytes, cerebellar granule cells, macrophages, mast cells, ovarian granulosa cells, retinal ganglia neurons and skeletal muscle cells. PEDF R is directly activated by PEDF, and indirectly by beta3-AR which promotes CGI-58 association. Human PEDF R shares 85% amino acid (aa) sequence identity with mouse and rat PEDF R within aa 162‑332, the region used as an immunogen.
Long Name
Alternate Names
Gene Symbol
UniProt
Additional PEDFR/PNPLA2 Products
Product Specific Notices for Human PEDFR/PNPLA2 Alexa Fluor® 488-conjugated Antibody
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only