Human Peptide YY Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB9456
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Accession # P10082
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human Peptide YY Antibody
Peptide YY in Human Pancreas.
Peptide YY was detected in immersion fixed paraffin-embedded sections of human pancreas using Rabbit Anti-Human Peptide YY Monoclonal Antibody (Catalog # MAB9456) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC003). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in islet cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.Applications for Human Peptide YY Antibody
Immunohistochemistry
Sample: Immersion fixed paraffin-embedded secitons of human pancreas
Formulation, Preparation, and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Peptide YY
Peptide YY (PYY), a secretory peptide, is expressed by L cells (enteroendocrine cells) in the small and large intestine, Islet of Langerhans cells, testis, and in some central and peripheral neurons. Because PYY is released from L cells after feeding, it is thought to produce a satiety signal. While the regulation of appetite by PYY and GLP-1 have been studied extensively, recent evidence supports a role for PYY in Islet of Langerhans beta cell survival. PYY secretion is also modulated by gut microbiota, and levels of colonic PYY have reduced in rats with DSS-induced colitis, and in humans with inflammatory bowel disease (IBD), while circulating PYY increased in IBD.
Alternate Names
Gene Symbol
UniProt
Additional Peptide YY Products
Product Documents for Human Peptide YY Antibody
Product Specific Notices for Human Peptide YY Antibody
For research use only