PC-3 human prostate cancer cell line was stained with Mouse Anti-Human Somatostatin R3/ SSTR3 Monoclonal Antibody (Catalog # MAB7018, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

Applications for Human Somatostatin R3/SSTR3 Antibody

Application

Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

2.5 µg/10⁶ cells
Sample: PC‑3 human prostate cancer cell line

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Sterile PBS to a final concentration of 0.5 mg/mL. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Somatostatin R3/SSTR3

Somatostatin Receptor 3 (SSTR3) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR3 shares 80% aa identity with mouse SSTR3 within the extracellular domains. SSTR3 protein has been detected in anterior pituitary, lymphocytes, thyroid, parathyroid, stomach, small intestine, and pancreatic islets. In neurons, it is located within cilia and is implicated in object recognition memory. It is an inhibitory receptor that transduces the antiproliferative and antisecretive effects of somatostatins in the pituitary.

Long Name

Somatostatin Receptor Type 3

Alternate Names

SomatostatinR3, SSR-28, SST3, SSTR3

Entrez Gene IDs

6753 (Human); 20607 (Mouse); 171044 (Rat)

Gene Symbol

SSTR3

UniProt

P32745

Additional Somatostatin R3/SSTR3 Products

Product Documents for Human Somatostatin R3/SSTR3 Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human Somatostatin R3/SSTR3 Antibody

For research use only

Citations
Reviews

Calculators
Flow Cytometry

Human Somatostatin R3/SSTR3 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB7018

Key Product Details

Species Reactivity

Validated:

Applications

Label

Antibody Source

View all Somatostatin R3/SSTR3 Antibodies »

Product Summary for Human Somatostatin R3/SSTR3 Antibody

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human Somatostatin R3/SSTR3 Antibody

Detection of SSTR3 in PC‑3 Human Cell Line by Flow Cytometry.