Human Survivin Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF6471
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry, Western Blot
Label
Biotin
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
E. coli-derived recombinant human Survivin
Specificity
Detects human Survivin in Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human Survivin Biotinylated Antibody
Application
Recommended Usage
Flow Cytometry
2.5 µg/106 cells
Sample: Human peripheral blood mononuclear cells
Sample: Human peripheral blood mononuclear cells
Western Blot
0.1 µg/mL
Sample: Recombinant Human Survivin Western Blot Standard (Catalog # WBC010B)
Sample: Recombinant Human Survivin Western Blot Standard (Catalog # WBC010B)
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Survivin
Survivin is a member of the Inhibitor of Apoptosis (IAP) gene family and contains a single BIR domain. Increased survivin expression at the G2/M checkpoint contributes to tissue homeostasis and differentiation during embryonic and fetal development. Increased expression in differentiated adult tissues, however, frequently results in unchecked cell survival, resulting in cancer. Survivin can protect cells from caspase-induced apoptosis activated in mitosis presumably by binding to Caspase-3, -7, and -9.
Additional Survivin Products
Product Documents for Human Survivin Biotinylated Antibody
Product Specific Notices for Human Survivin Biotinylated Antibody
For research use only
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