Human TCL1B Antibody
R&D Systems, part of Bio-Techne | Catalog # AF6794
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
E. coli-derived recombinant human TCL1B
Ala2-Asp128 (Glu93Arg)
Accession # O95988
Ala2-Asp128 (Glu93Arg)
Accession # O95988
Specificity
Detects human TCL1B in direct ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant human TCL1A is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Scientific Data Images for Human TCL1B Antibody
TCL1B in Human Lymphoma.
TCL1B was detected in immersion fixed paraffin-embedded sections of human lymphoma using Goat Anti-Human TCL1B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6794) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.Applications for Human TCL1B Antibody
Application
Recommended Usage
Immunohistochemistry
5-15 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human lymphoma
Sample: Immersion fixed paraffin-embedded sections of human lymphoma
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Sterile PBS to a final concentration of 0.2 mg/mL. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: TCL1B
TCL1B (T cell leukemia protein 1B; also SYN1 and [p15]TML1) is a monomeric,15 kDa (predicted) member of the TCL1 family of proteins. It is expressed in the embryo and syncytiotrophoblast, and interacts with Akt1 and Akt2 kinase, promoting their activation and the subsequent deactivation of proapoptotic molecules. Human TCL1B is 128 amino acids (aa) in length. There is no definitive structural motif that characterizes TCL1B, save for a unique beta-barrel configuration. Full length human TCL1B shares less than 35% aa identity with five orthologous mouse TCL1B isoforms.
Long Name
T Cell Leukemia Protein 1B
Alternate Names
MTCP1-like protein 1, SYN-1, TML1
Entrez Gene IDs
9623 (Human)
Gene Symbol
TCL1B
UniProt
Additional TCL1B Products
Product Documents for Human TCL1B Antibody
Product Specific Notices for Human TCL1B Antibody
For research use only
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