Human TEM8/ANTXR1 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB3886
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 371113
Product Specifications
Immunogen
E. coli-derived recombinant human TEM8/ANTXR1 isoform 1
Gln28-Gly320
Accession # Q9H6X2
Gln28-Gly320
Accession # Q9H6X2
Specificity
Detects human TEM8/ANTXR1 in direct ELISAs and Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human TEM8/ANTXR1 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human TEM8/ANTXR1
Sample: Recombinant Human TEM8/ANTXR1
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: TEM8/ANTXR1
Tumor Endothelial Marker 8 (TEM8), also called ATR1 and ANTXR1, is a glycoprotein of the anthrax toxin receptor family that is expressed by endothelial cells. Type I transmembrane isoforms of 564 aa (80‑85 kDa) and 368 aa (60 kDa) and potentially secreted isoforms of 330 aa and 297 aa (45 kDa) are differentially expressed. All diverge at the C-terminal end but share the N-terminal vWFA domain that binds the anthrax toxin PA subunit as well as collagens I and IV. Human TEM8 shares 99% aa identity with mouse and rat and 92% identity with dog and chick TEM8 within the extracellular domain.
Long Name
Tumor Endothelial Marker 8/Anthrax Toxin Receptor 1
Alternate Names
ANTXR1
Gene Symbol
ANTXR1
UniProt
Additional TEM8/ANTXR1 Products
Product Documents for Human TEM8/ANTXR1 Antibody
Product Specific Notices for Human TEM8/ANTXR1 Antibody
For research use only
Loading...
Loading...
Loading...
Loading...