HT-29 human colon adenocarcinoma cell line was stained with Mouse Anti-Human TM4SF4 APC-conjugated Monoclonal Antibody (Catalog # FAB7998A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human TM4SF4 APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: HT‑29 human colon adenocarcinoma cell line

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: TM4SF4

TM4SF4 (Transmembrane 4 L6 Family Member 4), also known as IL-TMP (Intestine and Liver Tetraspanin Membrane Protein), is a member of the L6 tetraspanin family of molecules. It is expressed at highest levels on non-proliferating villus-associated intestinal epithelia and periportal hepatocytes, with increased expression in hepatocellular carcinomas. It is thought to mediate proliferation and adhesion. Its molecular size is reported at approximately 21 kDa for the unglycosylated form and 25-40 kDa for various glycosylated forms. The 202 amino acid (aa) human TM4SF4 contains four transmembrane domains and two potential N-glycosylation sites. It shares 88% aa sequence identity with mouse and rat TM4SF4.

Long Name

Transmembrane 4 L Six Family Member 4

Alternate Names

ILTMP

Entrez Gene IDs

7104 (Human); 229302 (Mouse); 116467 (Rat)

Gene Symbol

TM4SF4

UniProt

P48230

Additional TM4SF4 Products

Product Documents for Human TM4SF4 APC-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

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Product Specific Notices for Human TM4SF4 APC-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human TM4SF4 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB7998A

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all TM4SF4 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human TM4SF4 APC-conjugated Antibody

Detection of TM4SF4 in HT‑29 Human Cell Line by Flow Cytometry.