Human TMEFF1/Tomoregulin-1 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB1919

R&D Systems, part of Bio-Techne
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MAB1919
MAB1919-SP
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 249511

View all TMEFF1/Tomoregulin-1 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human TMEFF1/Tomoregulin‑1
Ser40-Thr328
Accession # Q8IYR6

Specificity

Detects human TMEFF1/Tomoregulin‑1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no  cross-reactivity with recombinant mouse TMEFF1 or recombinant human TMEFF2 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human TMEFF1/Tomoregulin-1 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human TMEFF1/Tomoregulin-1

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TMEFF1/Tomoregulin-1

TMEFF1 (Transmembrane protein with EGF-like and two Follistatin-like domains 1), also known as tomoregulin 1 is a type I transmembrane glycoprotein that contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain can be released as a soluble protein. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.

Long Name

Transmembrane Protein with EFG-like and two Follistatin-like Domains

Alternate Names

C9orf2, Tomoregulin-1, Tomoregulin1

Entrez Gene IDs

8577 (Human); 230157 (Mouse)

Gene Symbol

TMEFF1

UniProt

Q8IYR6

Additional TMEFF1/Tomoregulin-1 Products

Product Documents for Human TMEFF1/Tomoregulin-1 Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human TMEFF1/Tomoregulin-1 Antibody

For research use only

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