Human Vitamin D BP Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB3778
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 359501
Product Specifications
Immunogen
Human plasma-derived Vitamin D BP
Accession # P02774
Accession # P02774
Specificity
Detects human plasma-derived Vitamin D BP in direct ELISAs and Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human Vitamin D BP Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Human plasma-derived Vitamin D BP
Sample: Human plasma-derived Vitamin D BP
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Reviewed Applications
Read 1 review rated 5 using MAB3778 in the following applications:
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Vitamin D BP
Vitamin D BP (VitD BP), also called VDB, DBP, Group Specific Component (Gc) or macrophage-activating factor (DBP- or Gc-MAF), is a member of the albumin family. These plasma/body fluid proteins have a conserved pattern of cysteine motifs that form binding domains. VitD BP is predominantly produced by hepatic parenchymal cells. It transports VitD, activates macrophages and osteoclasts, and enhances C5a chemotactic activity. Over 80 variant alleles have been identified, some of which correlate with osteoporosis or prostate cancer. Human and mouse VitD BP share 78% aa identity.
Long Name
Vitamin D Binding Protein
Alternate Names
DBP, DBP-MAF, Gc, Gc-MAF, VDBG, VDBP
Gene Symbol
GC
UniProt
Additional Vitamin D BP Products
Product Documents for Human Vitamin D BP Antibody
Product Specific Notices for Human Vitamin D BP Antibody
For research use only
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