Humanin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56876

Novus Biologicals, part of Bio-Techne
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NB100-56876
NB100-56876SS
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all Humanin Antibodies »

Product Specifications

Immunogen

Amino acids 12-24 of human humanin protein were used as the immunogen.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Humanin Antibody

Western Blot: Humanin Antibody [NB100-56876]

Western Blot: Humanin Antibody [NB100-56876]

Western Blot: Humanin Antibody [NB100-56876] - Analysis of human humanin in (A) recombinant fusion protein containing amino acids 12-24 and (B) fusion partner without these amino acids, using this antibody.

Applications for Humanin Antibody

Application
Recommended Usage

ELISA

1:100-1:1000

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera with 50% Glycerol

Preservative

0.025% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Humanin

Humanin is a novel 24 A.A polypeptide identified in Alzheimer's disease-affected brain. It is 99% homologous to mitochondrial 16s ribosomal RNA and functions as a novel neuroprotective and cytoprotective factor. It specifically inhibits neuronal cell death induced by beta-amyloids and Alzheimer's disease causing FAD genes by competitively inhibiting access of FPRL1 receptor to beta-amyloids. It acts as an anti-apoptotic factor by binding to Bcl-2/Bax family of pro-apoptotic factors including Bax, Bak, Bid and BimEL and inhibits their pro-apoptotic activity. It activates JAK/STAT signaling pathway and is regulated by TRIM11. It interacts with IGFBP-3 and specifically blocks IGFBP-3 induced cell death in glioblastoma cells. Humanin is also expressed in colon and testis.

Alternate Names

HN, HUNIN

Gene Symbol

MTRNR2L1

UniProt

Q8IVG9 (Human)

Additional Humanin Products

Product Documents for Humanin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Humanin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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