Humanin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56877

Novus Biologicals, part of Bio-Techne
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NB100-56877
NB100-56877SS
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Key Product Details

Species Reactivity

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all Humanin Antibodies »

Product Specifications

Immunogen

The full length peptide sequence from the human MT-RNR2 protein (accesion number Q8IVG9).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Humanin Antibody

Western Blot: Humanin Antibody [NB100-56877]

Western Blot: Humanin Antibody [NB100-56877]

Western Blot: Humanin Antibody [NB100-56877] - Analysis of Humanin in (A) recombinant fusion protein containing amino acids 1-24 and (B) fusion partner without these amino acids, using Humanin antibody at 1:2000.
Immunohistochemistry-Paraffin: Humanin Antibody [NB100-56877]

Immunohistochemistry-Paraffin: Humanin Antibody [NB100-56877]

Immunohistochemistry-Paraffin: Humanin Antibody [NB100-56877] - Analysis Humanin in human testis at 1:100.

Applications for Humanin Antibody

Application
Recommended Usage

ELISA

1:100-1:1000

Immunocytochemistry/ Immunofluorescence

reported by customer review

Immunohistochemistry-Paraffin

1:100

Western Blot

1:500-1:2000

Reviewed Applications

Read 1 review rated 3 using NB100-56877 in the following applications:

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera with 50% Glycerol

Preservative

0.025% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Humanin

Humanin is a novel 24 A.A polypeptide identified in Alzheimer's disease-affected brain. It is 99% homologous to mitochondrial 16s ribosomal RNA and functions as a novel neuroprotective and cytoprotective factor. It specifically inhibits neuronal cell death induced by beta-amyloids and Alzheimer's disease causing FAD genes by competitively inhibiting access of FPRL1 receptor to beta-amyloids. It acts as an anti-apoptotic factor by binding to Bcl-2/Bax family of pro-apoptotic factors including Bax, Bak, Bid and BimEL and inhibits their pro-apoptotic activity. It activates JAK/STAT signaling pathway and is regulated by TRIM11. It interacts with IGFBP-3 and specifically blocks IGFBP-3 induced cell death in glioblastoma cells. Humanin is also expressed in colon and testis.

Alternate Names

HN, HUNIN

Gene Symbol

MTRNR2L1

UniProt

Q8IVG9 (Human)

Additional Humanin Products

Product Documents for Humanin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Humanin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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