Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all HVEM/TNFRSF14 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TNFRSF14. The immunogen is located within the last 50 amino acids of TNFRSF14. Amino Acid Squence: VQRKRQEAEGEATVIE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HVEM/TNFRSF14 Antibody - BSA Free

Western Blot: HVEM/TNFRSF14 AntibodyBSA Free [NBP1-76689]

Western Blot: HVEM/TNFRSF14 AntibodyBSA Free [NBP1-76689]

Western Blot: HVEM/TNFRSF14 Antibody [NBP1-76689] - Analysis of 5 ng of TNFRSF14 with TNFRSF14 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: HVEM/TNFRSF14 Antibody - BSA Free [NBP1-76689]

Immunocytochemistry/ Immunofluorescence: HVEM/TNFRSF14 Antibody - BSA Free [NBP1-76689]

Immunocytochemistry/Immunofluorescence: HVEM/TNFRSF14 Antibody [NBP1-76689] - Immunofluorescence of TNFRSF14 in Raji cells with TNFRSF14 antibody at 20 ug/mL.
Western Blot: HVEM/TNFRSF14 AntibodyBSA Free [NBP1-76689]

Western Blot: HVEM/TNFRSF14 AntibodyBSA Free [NBP1-76689]

Western Blot: HVEM/TNFRSF14 Antibody [NBP1-76689] - Raji cell lysate with TNFRSF14 antibody at 2 u/mL in (A) the absence and (B) the presence of blocking peptide.
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Applications for HVEM/TNFRSF14 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10-20 ug/ml

Western Blot

2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HVEM/TNFRSF14

Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappaB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Long Name

Herpesvirus Entry Mediator

Alternate Names

ATAR, CD270, LIGHTR, TNFRSF14

Gene Symbol

TNFRSF14

UniProt

Q92956

Additional HVEM/TNFRSF14 Products

Product Documents for HVEM/TNFRSF14 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HVEM/TNFRSF14 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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