HYAL2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-21609

Novus Biologicals, part of Bio-Techne
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NBP2-21609
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (91%), Porcine (93%), Rhesus Macaque (100%), Sheep (91%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Hyaluronidase 2/HYAL2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human HYAL2. The exact sequence is proprietary.

Reactivity Notes

Mouse (88%), Rat (87%).

Localization

Cell membrane; Lipid-anchor; GPI-anchor

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HYAL2 Antibody

Western Blot: HYAL2 Antibody [NBP2-21609]

Western Blot: HYAL2 Antibody [NBP2-21609]

Western Blot: HYAL2 Antibody [NBP2-21609] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE gel, diluted at 1:1000.

Applications for HYAL2 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Hyaluronidase 2/HYAL2

This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. Varying functions have been described for this protein. It has been described as a lysosomal hyaluronidase which is active at a pH below 4 and specifically hydrolyzes high molecular weight hyaluronan. It has also been described as a GPI-anchored cell surface protein which does not display hyaluronidase activity but does serve as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR. [provided by RefSeq]

Long Name

Hyaluronoglucosaminidase-2

Alternate Names

HYAL-2, LUCA-2, LUCA2

Gene Symbol

HYAL2

UniProt

Q12891 (Human)

Additional Hyaluronidase 2/HYAL2 Products

Product Documents for HYAL2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HYAL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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