HYPB Antibody (CL9956)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-88941

Novus Biologicals, part of Bio-Techne
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NBP2-88941
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL9956

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HYPB Antibodies »

Product Summary for HYPB Antibody (CL9956)

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids: PHHPFAGYPPGYPMQAYVDPSNPN

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HYPB Antibody (CL9956)

Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941]

Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941]

Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941]

Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941]

Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941] - Staining of human cervix, uterine shows moderate to strong nuclear positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941]

Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941]

Immunohistochemistry-Paraffin: HYPB Antibody (CL9956) [NBP2-88941] - Staining of human endometrium shows moderate nuclear positivity in glandular cells.
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Applications for HYPB Antibody (CL9956)

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HYPB

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. (provided by RefSeq)

Alternate Names

FLJ22472, FLJ23184, FLJ45883, FLJ46217, HIF1, HIF-1EC 2.1.1.43, HIP-1, histone-lysine N-methyltransferase SETD2, hSET2, huntingtin interacting protein 1, Huntingtin yeast partner B, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, HYPBp231HBP, KIAA1732SET domain-containing protein 2, KMT3AHBP231, Lysine N-methyltransferase 3A, SET domain containing 2, SET2FLJ16420

Gene Symbol

SETD2

Additional HYPB Products

Product Documents for HYPB Antibody (CL9956)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HYPB Antibody (CL9956)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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