IA-2/PTPRN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59411

Novus Biologicals, part of Bio-Techne
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NBP1-59411
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all IA-2/PTPRN Antibodies »

Product Summary for IA-2/PTPRN Antibody

Immunogen

Synthetic peptides corresponding to PTPRN(protein tyrosine phosphatase, receptor type, N) The peptide sequence was selected from the middle region of PTPRN. Peptide sequence EVQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAE. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for IA-2/PTPRN Antibody

Western Blot: IA-2/PTPRN Antibody [NBP1-59411]

Western Blot: IA-2/PTPRN Antibody [NBP1-59411]

Western Blot: IA-2/PTPRN Antibody [NBP1-59411] - HepG2 cell lysate, concentration 0.0625ug/ml.
Western Blot: IA-2/PTPRN Antibody [NBP1-59411]

Western Blot: IA-2/PTPRN Antibody [NBP1-59411]

Western Blot: IA-2/PTPRN Antibody [NBP1-59411] - Human Kidney, Antibody Dilution: 0.5 ug/ml.

Applications for IA-2/PTPRN Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IA-2/PTPRN

PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.

Long Name

Islet Cell Antigen 2/Protein Tyrosine Phosphatase Receptor-type N

Alternate Names

IA2, ICA512, PTPRN, R-PTP-N

Gene Symbol

PTPRN

UniProt

Q7KZS4 (Human)

Additional IA-2/PTPRN Products

Product Documents for IA-2/PTPRN Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IA-2/PTPRN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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