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ID1 Antibody (CL11981)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21206

Novus Biologicals, part of Bio-Techne
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NBP3-21206-100ul
NBP3-21206-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL11981

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ID1 Antibody (CL11981)

Immunogen

This antibody was developed against a Synthetic Peptide of P41134. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for ID1 Antibody (CL11981)

Immunohistochemistry-Paraffin: ID1 Antibody [NBP3-21206] -

Immunohistochemistry-Paraffin: ID1 Antibody [NBP3-21206] -

Staining of human liver shows weak nuclear positivity in hepatocytes.
Immunohistochemistry-Paraffin: ID1 Antibody [NBP3-21206] -

Immunohistochemistry-Paraffin: ID1 Antibody [NBP3-21206] -

Staining of human glioblastoma multiforme shows strong positivity in tumor cells.
Immunohistochemistry-Paraffin: ID1 Antibody [NBP3-21206] -

Immunohistochemistry-Paraffin: ID1 Antibody [NBP3-21206] -

Staining of human cerebral cortex shows strong nuclear positivity in neurons.

Applications for ID1 Antibody (CL11981)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ID1

Id1 is encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

Inhibitor of DNA Binding 1

Alternate Names

BHLHB24, bHLHb24DNA-binding protein inhibitor ID-1, Class B basic helix-loop-helix protein 24, dJ857M17.1.2, dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helixprotein), ID, inhibitor of differentiation 1, Inhibitor of DNA binding 1, inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

Gene Symbol

ID1

Additional ID1 Products

Product Documents for ID1 Antibody (CL11981)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ID1 Antibody (CL11981)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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