IFI16 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24908

Novus Biologicals, part of Bio-Techne
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NBP3-24908
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IFI16 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein IFI16 using the following amino acid sequence: STPSSSFLTTKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IFI16 Antibody

IFI16 Antibody Western Blot: IFI16 Antibody [NBP3-24908]

Western Blot: IFI16 Antibody [NBP3-24908]

Analysis in human cell line RT-4 and human cell line U-251 MG.
IFI16 Antibody Immunocytochemistry/Immunofluorescence: IFI16 Antibody [NBP3-24908]

Immunocytochemistry/Immunofluorescence: IFI16 Antibody [NBP3-24908]

Staining of human cell line SK-MEL-30 shows localization to nucleoplasm.

Applications for IFI16 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml

Western Blot

0.04-0.4 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IFI16

IFI16 encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway.

Alternate Names

ifi-16, IFNGIP1gamma-interferon-inducible protein 16, interferon, gamma-inducible protein 16, interferon-gamma induced protein IFI 16, Interferon-inducible myeloid differentiation transcriptional activator, MGC9466, PYHIN2

Gene Symbol

IFI16

Additional IFI16 Products

Product Documents for IFI16 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IFI16 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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