IFN-gamma, a type II interferon and an acid-labile interferon, is mainly produced by CD4 and CD8 T-lymphocytes and natural killer cells activated by antigens, mitogens or alloantigens. IFN-gamma shows no significant homology with IFN-beta or IFN-alpha. IFN-gamma has antiviral and antiparasitic activities and exhibits also immunoregulatory and proinflammatory activities. IFN-gamma induces cytokine production and promotes antigen presentation by up regulating the expression of MHC proteins as well as other antigen proteins. In contrast to other interferons, which are mostly antiviral, the main activity of IFN-gamma seems to be immunomodulatory. Human IFN-gamma is species-specific and is only biologically active in human and primate cells.

Long Name

Interferon gamma

Alternate Names

IFG, IFI, IFNG, IFNgamma

Gene Symbol

IFNG

Additional IFN-gamma Products

Product Documents for IFN-gamma Antibody (IFNG/466) [Janelia Fluor® 549]

Product Datasheets

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COA

SDS

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Product Specific Notices for IFN-gamma Antibody (IFNG/466) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IFN-gamma Antibody (IFNG/466) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-54394JF549

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

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Product Specifications

Immunogen

Localization

Clonality

Host

Isotype

Applications for IFN-gamma Antibody (IFNG/466) [Janelia Fluor® 549]

CyTOF-ready

Immunohistochemistry

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: IFN-gamma