IgE Antibody (4H10) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NB500-472
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
ELISA, Flow (Cell Surface), Flow Cytometry, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 4H10
Format
BSA Free
Concentration
1.0 mg/ml
Product Summary for IgE Antibody (4H10) - BSA Free
Immunogen
Purified human IgE.
Specificity
The antibody 4H10 reacts with human IgE; it recognizes an epitope different from the ones recognized by BE5 and 4G7 antibodies to IgE.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for IgE Antibody (4H10) - BSA Free
Flow (Cell Surface): IgE Antibody (4H10) - BSA Free [NB500-472]
Flow (Cell Surface): IgE Antibody (4H10) [NB500-472] - Surface staining of IgE on human peripheral blood cells with anti-IgE (4H10) purified, GAM-APC.Flow Cytometry: IgE Antibody (4H10) - BSA Free [NB500-472]
Flow Cytometry: IgE Antibody (4H10) [NB500-472] - Staining of IgE on human peripheral blood cells with anti-IgE (4H10) FITC.Applications for IgE Antibody (4H10) - BSA Free
Application
Recommended Usage
ELISA
1:2000
Flow Cytometry
4 ug/ml
Application Notes
Purity is > 95% (by SDS-PAGE). This antibody recognizes an epitope different from the one recognized by ab773 and ab775.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS (pH 7.4)
Format
BSA Free
Preservative
0.9% Sodium Azide
Concentration
1.0 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C. Do not freeze.
Background: IgE
There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans.
IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.
Long Name
Immunoglobulin E
Alternate Names
IgE, immunoglobulin heavy constant epsilon
Entrez Gene IDs
3497 (Human)
Gene Symbol
IGHE
Additional IgE Products
Product Documents for IgE Antibody (4H10) - BSA Free
Product Specific Notices for IgE Antibody (4H10) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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