IGF2BP3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16930

Novus Biologicals, part of Bio-Techne
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NBP2-16930
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IGF2BP3 Antibodies »

Product Summary for IGF2BP3 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human IGF2BP3. The exact sequence is proprietary.

Localization

Nucleus; Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IGF2BP3 Antibody

Western Blot: IGF2BP3 Antibody [NBP2-16930]

Western Blot: IGF2BP3 Antibody [NBP2-16930]

Western Blot: IGF2BP3 Antibody [NBP2-16930] - Sample (30 ug of whole cell lysate) A: PC-3 B: SK-N-SH 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: IGF2BP3 Antibody [NBP2-16930]

Immunocytochemistry/ Immunofluorescence: IGF2BP3 Antibody [NBP2-16930]

Immunocytochemistry/Immunofluorescence: IGF2BP3 Antibody [NBP2-16930] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: IMP3 protein stained by IMP3 antibody diluted at 1:500. Blue: Hoechst 33342 staining.
Immunohistochemistry-Paraffin: IGF2BP3 Antibody [NBP2-16930]

Immunohistochemistry-Paraffin: IGF2BP3 Antibody [NBP2-16930]

Immunohistochemistry-Paraffin: IGF2BP3 Antibody [NBP2-16930] - Hela xenograft, using IMP-3 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for IGF2BP3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IGF2BP3

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq]

Alternate Names

CT98, hKOC, IGF II mRNA binding protein 3, IGF2 mRNA-binding protein 3, IGF-II mRNA-binding protein 3, IMP-3KH domain-containing protein overexpressed in cancer, IMP3VICKZ family member 3, insulin-like growth factor 2 mRNA binding protein 3, insulin-like growth factor 2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KOC1DKFZp686F1078, VICKZ3cancer/testis antigen 98

Gene Symbol

IGF2BP3

UniProt

O00425 (Human)

Additional IGF2BP3 Products

Product Documents for IGF2BP3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IGF2BP3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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