IGFBP-1 Antibody (C1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43258

Novus Biologicals, part of Bio-Techne
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NBP3-43258
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C1

Concentration

1 mg/ml

View all IGFBP-1 Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human IGFBP-1 (Uniprot#: P08833; Glu36~Asn235)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for IGFBP-1 Antibody (C1)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20 ug/mL

Immunohistochemistry

5-20 ug/mL

Western Blot

0.01-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, pH7.4, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IGFBP-1

IGFBP1 is a gene that codes for an IGF-binding protein that circulates in the plasma and prolongs the half-life of IGFs and works to either inhibit of stimulate the growth promoting effects while also promoting cell migration and has a length of 259 amino acids and a weight of approximately 28 kDa. Current studies are being done on several diseases and disorders relating to this gene including protein-energy malnutrition, pre-eclampsia, persistent fetal circulation syndrome, Silver-Russell syndrome, growth hormone deficiency, Ehlers-Danlos syndrome, glucose intolerance, Prader-Willi syndrome, and chronic fatigue syndrome. IGFBP1 has also been shown to have interactions with IGF1, IGF2, MMP26, TF, and ARNT in pathways such as the myometrial relaxation and contraction, HIF-1-alpha transcription factor, IGF regulation, and protein metabolism pathways.

Long Name

Insulin-like Growth Factor Binding Protein 1

Alternate Names

IGFBP1

Gene Symbol

IGFBP1

Additional IGFBP-1 Products

Product Documents for IGFBP-1 Antibody (C1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IGFBP-1 Antibody (C1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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