IGFBP-2 Antibody (CL13565)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24569

Novus Biologicals, part of Bio-Techne
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NBP3-24569-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL13565

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IGFBP-2 Antibodies »

Product Summary for IGFBP-2 Antibody (CL13565)

Immunogen

This antibody was designed to target the recombinant protein IGFBP-2, with the precise immunogen sequence being withheld for proprietary reasons.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for IGFBP-2 Antibody (CL13565)

Immunohistochemistry-Paraffin: IGFBP-2 Antibody (CL13565) [NBP3-24569]

Staining of human kidney shows strong membranous positivity in cells in tubules and cells in glomeruli with additional cytoplasmic positivity.

Immunohistochemistry-Paraffin: IGFBP-2 Antibody (CL13565) [NBP3-24569]

Analysis in human pancreas and skin tissues using NBP3-24569 antibody. Corresponding IGFBP2 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: IGFBP-2 Antibody (CL13565) [NBP3-24569]

Staining of human stomach shows strong membranous positivity in glandular cells.
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Applications for IGFBP-2 Antibody (CL13565)

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000 - 1:10000
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IGFBP-2

IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is over expressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The over expression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Long Name

Insulin-like Growth Factor Binding Protein 2

Alternate Names

IGFBP2

Gene Symbol

IGFBP2

Additional IGFBP-2 Products

Product Documents for IGFBP-2 Antibody (CL13565)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IGFBP-2 Antibody (CL13565)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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