IGFBP-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57978

Novus Biologicals, part of Bio-Techne
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NBP2-57978
NBP2-57978-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IGFBP-2 Antibodies »

Product Summary for IGFBP-2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ('GLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDS',)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IGFBP-2 Antibody

Immunocytochemistry/ Immunofluorescence: IGFBP-2 Antibody [NBP2-57978]

Immunocytochemistry/ Immunofluorescence: IGFBP-2 Antibody [NBP2-57978]

Immunocytochemistry/Immunofluorescence: IGFBP-2 Antibody [NBP2-57978] - Staining of human cell line U-2 OS shows localization to endoplasmic reticulum.

Applications for IGFBP-2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IGFBP-2

IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is over expressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The over expression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Long Name

Insulin-like Growth Factor Binding Protein 2

Alternate Names

IGFBP2

Gene Symbol

IGFBP2

Additional IGFBP-2 Products

Product Documents for IGFBP-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IGFBP-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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