IGFBP-5 Antibody (RM0097-12C23) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-22453

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2 Clone # RM0097-12C23

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all IGFBP-5 Antibodies »

Product Specifications

Immunogen

Mouse recombinant protein of IGFBP-5

Specificity

No cross activity to other mouse IGFBPs.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Scientific Data Images for IGFBP-5 Antibody (RM0097-12C23) - Azide and BSA Free

Immunohistochemistry-Paraffin: IGFBP-5 Antibody (RM0097-12C23) - Azide and BSA Free [NBP1-22453]

Immunohistochemistry-Paraffin: IGFBP-5 Antibody (RM0097-12C23) - Azide and BSA Free [NBP1-22453]

Immunohistochemistry-Paraffin: IGFBP-5 Antibody (RM0097-12C23) [NBP1-22453] - The Kidney tissue samples from the Folic Acid induced kidney injury model were fixed using 4% PFA at 4C for overnight and embeded in paraffin. 4um section was sublected to IHC with NBP1-22453

Applications for IGFBP-5 Antibody (RM0097-12C23) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IGFBP-5

IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.

Long Name

Insulin-like Growth Factor Binding Protein 5

Alternate Names

IGFBP5

Entrez Gene IDs

16011 (Mouse)

Gene Symbol

IGFBP5

UniProt

Q07079

Additional IGFBP-5 Products

Product Documents for IGFBP-5 Antibody (RM0097-12C23) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IGFBP-5 Antibody (RM0097-12C23) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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