IgG Heavy Chain Antibody (IG507R)
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-53145
Recombinant Monoclonal Antibody.
![Immunohistochemistry-Paraffin: IgG Heavy Chain Antibody (IG507R) [NBP2-53145]](https://resources.bio-techne.com/images/products/IgG-Heavy-Chain-Antibody-IG507R-Immunohistochemistry-Paraffin-NBP2-53145-img0001.jpg "Immunohistochemistry-Paraffin: IgG Heavy Chain Antibody (IG507R) [NBP2-53145]")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # IG507R
Concentration
0.2 mg/ml
Product Specifications
Immunogen
Recombinant full-length human IgG Heavy Chain protein
Localization
Cytoplasm, Cell Surface and Secreted
Specificity
Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Marker
B-Cell Marker
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
75 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
200ug/ml of recombinant antibody purified by Protein A. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-54458)
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
Scientific Data Images for IgG Heavy Chain Antibody (IG507R)
Immunohistochemistry-Paraffin: IgG Heavy Chain Antibody (IG507R) [NBP2-53145]
Immunohistochemistry-Paraffin: IgG Heavy Chain Antibody (IG507R) [NBP2-53145] - Formalin-fixed, paraffin-embedded human Tonsil stained with Anti-human IgG Heavy Chain Recombinant Rabbit Monoclonal Antibody (IG507R)![Protein Array: IgG Heavy Chain Antibody (IG507R) [NBP2-53145]](https://resources.bio-techne.com/images/products/IgG-Heavy-Chain-Antibody-IG507R-Protein-Array-NBP2-53145-img0003.jpg "Protein Array: IgG Heavy Chain Antibody (IG507R) [NBP2-53145]")
Protein Array: IgG Heavy Chain Antibody (IG507R) [NBP2-53145]
Protein Array: IgG Heavy Chain Antibody (IG507R) [NBP2-53145] - Analysis of Protein Array containing more than 19,000 full-length human proteins using IgG Heavy Chain Antibody (IG507R).Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5.Applications for IgG Heavy Chain Antibody (IG507R)
Application
Recommended Usage
Immunohistochemistry-Paraffin
1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Optimal dilution for a specific application should be determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: IgG Heavy Chain
Alternate Names
Immunoglobulin G, ImmunoglobulinG
UniProt
Additional IgG Heavy Chain Products
Product Documents for IgG Heavy Chain Antibody (IG507R)
Product Specific Notices for IgG Heavy Chain Antibody (IG507R)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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