IL-17/IL-17A Antibody (408H6.01/mAb25)

Novus Biologicals, part of Bio-Techne | Catalog # DDX0336P-100

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Block/Neutralize, ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 408H6.01/mAb25

Concentration

0.5 mg/ml

View all IL-17/IL-17A Antibodies »

Product Specifications

Immunogen

IL17A was used as immunogen.

Reactivity Notes

Human, Mouse

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for IL-17/IL-17A Antibody (408H6.01/mAb25)

Western Blot: IL-17/IL-17A Antibody (408H6.01/mAb25) [DDX0336P-100]

Western Blot: IL-17/IL-17A Antibody (408H6.01/mAb25) [DDX0336P-100]

Western Blot: IL-17/IL-17A Antibody (408H6.01/mAb25) [DDX0336P-100] - 1-Human IL17 is a N -glycosylated dimer.2-Human IL17 digested by endoglycosidase -F.
Flow Cytometry: IL-17/IL-17A Antibody (408H6.01/mAb25) [DDX0336P-100]

Applications for IL-17/IL-17A Antibody (408H6.01/mAb25)

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:10-1:1000

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IL-17/IL-17A

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRalpha/beta+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).

Long Name

Interleukin 17

Alternate Names

CTLA-8, CTLA8, IL-17A, IL17, IL17A

Gene Symbol

IL17A

Additional IL-17/IL-17A Products

Product Documents for IL-17/IL-17A Antibody (408H6.01/mAb25)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-17/IL-17A Antibody (408H6.01/mAb25)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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