IL-17E/IL-25 Antibody (68C1039.2) - Azide Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33223

Novus Biologicals, part of Bio-Techne
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NBP2-33223
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Catalog #
BSA Free
NB100-56541
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 68C1039.2

Format

Azide Free

Concentration

1.0 mg/ml

View all IL-17E/IL-25 Antibodies »

Product Summary for IL-17E/IL-25 Antibody (68C1039.2) - Azide Free

Immunogen

Amino acids 115-132 of human IL-17E (isoform CRA_a) were used as immunogen for this antibody.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-17E/IL-25 Antibody (68C1039.2) - Azide Free

Western Blot: IL-17E/IL-25 Antibody (68C1039.2)Azide Free [NBP2-33223]

Western Blot: IL-17E/IL-25 Antibody (68C1039.2)Azide Free [NBP2-33223]

Western Blot: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223] - Analysis of IL-17E using IL-17E monoclonal antibody. Mouse testis lysate probed with IL-17E antibody at 2 ug/mL. Image from the standard format of this antibody.
Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223]

Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223]

Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223] - Tissue section of mouse kidney using IL17E/IL25 antibody clone 68C1039.2 at 1:150. The antibody generated a diffused cytoplasmic staining in the tubular and ductal epithelia cells, and a strong positivity in the inter-tubular/ductal blood vessels. Image f
Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223]

Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223]

Immunohistochemistry: IL-17E/IL-25 Antibody (68C1039.2) - Azide Free [NBP2-33223] - Adrenal cortex, Human Image from the standard format of this antibody.
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Applications for IL-17E/IL-25 Antibody (68C1039.2) - Azide Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:1000

Immunohistochemistry-Paraffin

1:10-1:500. Use reported in scientific literature (Terrier B et al)

Western Blot

2-4 ug/ml
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS - BSA free

Format

Azide Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-17E/IL-25

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E (2). IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis (3), multiple sclerosis (4), and promotion of tumor growth (5). IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated by Shi, et al (6) and Lee, et al. (2) and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8.

Long Name

Interleukin 17E

Alternate Names

IL-25, IL17E, IL25

Gene Symbol

IL25

Additional IL-17E/IL-25 Products

Product Documents for IL-17E/IL-25 Antibody (68C1039.2) - Azide Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for IL-17E/IL-25 Antibody (68C1039.2) - Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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