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IL-17RB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85450

Novus Biologicals, part of Bio-Techne
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NBP1-85450

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPG

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-17RB Antibody

Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450]

Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450]

Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Analysis in human kidney and skeletal muscle tissues using NBP1-85450 antibody. Corresponding IL17RB RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450]

Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450]

Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450]

Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450]

Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Applications for IL-17RB Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-17RB

IL17B Receptor is encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Long Name

Interleukin 17B Receptor

Alternate Names

Evi27, IL-17 RB, IL-17 RH1, IL-17ER, IL17RB

Gene Symbol

IL17RB

Additional IL-17RB Products

Product Documents for IL-17RB Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-17RB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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