IL-20R alpha Antibody (024)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89468

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 024

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-20R alpha Antibodies »

Product Summary for IL-20R alpha Antibody (024)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-20R alpha (Accession#: NP_055247.3; Met 1-Lys 250).

Specificity

No cross-reactivity in ELISA with: Human IFNgR1Human IL10RB

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for IL-20R alpha Antibody (024)

Immunohistochemistry-Paraffin: IL-20R alpha Antibody (024) [NBP2-89468]

Immunohistochemistry-Paraffin: IL-20R alpha Antibody (024) [NBP2-89468]

Immunohistochemistry-Paraffin: IL-20R alpha Antibody (024) [NBP2-89468] - Staining of human IL20Ra in human skin with rabbit monoclonal antibody (1:200). Positive staining was localized to stratified squamous epithelium.

Applications for IL-20R alpha Antibody (024)

Application
Recommended Usage

ELISA

1:1000-1:2000

Immunohistochemistry-Paraffin

1:100-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-20R alpha

Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA, is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.

Long Name

Interleukin 20 Receptor alpha

Alternate Names

CRF2-8, IL-20 R alpha, IL-20R1, IL-20Ra, IL20R alpha, IL20RA, zcytor7

Gene Symbol

IL20RA

Additional IL-20R alpha Products

Product Documents for IL-20R alpha Antibody (024)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for IL-20R alpha Antibody (024)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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