IL-22 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31215

Novus Biologicals, part of Bio-Techne
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NBP2-31215
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-22 Antibodies »

Product Specifications

Immunogen

A synthetic peptide (QSSNFENILTWDSGPE) corresponding to amino acids 31 to 46 of the human IL-22R precursor was used as immunogen, GenBank no. ref [NP_067081.2]

Reactivity Notes

Predicted to react with Mouse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-22 Antibody

Western Blot: IL-22 Antibody [NBP2-31215]

Western Blot: IL-22 Antibody [NBP2-31215]

Western Blot: IL22 Antibody - Analysis of IL-22R expression in human HepG2 cell lysate at 1 ug /ml.
Immunocytochemistry/ Immunofluorescence: IL-22 Antibody [NBP2-31215]

Immunocytochemistry/ Immunofluorescence: IL-22 Antibody [NBP2-31215]

Immunocytochemistry/Immunofluorescence: IL22 Antibody - Staining of IL-22R in formalin-fxed HepG2 cells at 10 ig/ml

Applications for IL-22 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

10 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

No buffer

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: IL-22

Interleukin-22 (IL-22 or IL-TIF (IL-10-related T-cell derived inducible factor)) belongs to the IL-10 family of regulatory cytokines which also includes IL-10, IL-19, IL-20, IL-24 and IL-26. IL-22 is produced by T lymphocytes following anti-CD3 stimulation. It inhibits IL-4 production of Th2 cells, activates STAT-1 and STAT-3 in several hepatoma cell lines and upregulates the production of acute phase proteins. It may also be involved in inflammatory responses. Human and mouse IL-22 share 79% amino acid identity. Recombinant human IL-22 is a non-disulfide linked homodimer, signaling through a receptor complex of two subunits, IL-22R and IL-10R-beta, belonging to the class II cytokine receptor family.

Long Name

Interleukin 22

Alternate Names

IL-TIF, IL22

Gene Symbol

IL22

UniProt

Q9GZX6

Additional IL-22 Products

Product Documents for IL-22 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-22 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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