IL-27R alpha/WSX-1/TCCR Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76728

Novus Biologicals, part of Bio-Techne
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NBP1-76728
NBP1-76728SS
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all IL-27 R alpha/WSX-1/TCCR Antibodies »

Product Specifications

Immunogen

Antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor. The immunogen is located within the first 50 amino acids of TCCR. Amino Acid Squence: GSAGPLQCYGVGPLGD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-27R alpha/WSX-1/TCCR Antibody - BSA Free

Western Blot: IL-27R alpha/WSX-1/TCCR AntibodyBSA Free [NBP1-76728]

Western Blot: IL-27R alpha/WSX-1/TCCR AntibodyBSA Free [NBP1-76728]

Western Blot: IL-27R alpha/WSX-1/TCCR Antibody [NBP1-76728] - Analysis of IL27RA expression in human spleen tissue lysates with anti-IL27RA using NBP1-76728 at 1 ug /ml.
Immunocytochemistry/ Immunofluorescence: IL-27R alpha/WSX-1/TCCR Antibody - BSA Free [NBP1-76728]

Immunocytochemistry/ Immunofluorescence: IL-27R alpha/WSX-1/TCCR Antibody - BSA Free [NBP1-76728]

Immunocytochemistry/Immunofluorescence: IL-27R alpha/WSX-1/TCCR Antibody [NBP1-76728] - in A549 cells.
Immunohistochemistry-Paraffin: IL-27R alpha/WSX-1/TCCR Antibody - BSA Free [NBP1-76728]

Immunohistochemistry-Paraffin: IL-27R alpha/WSX-1/TCCR Antibody - BSA Free [NBP1-76728]

Immunohistochemistry-Paraffin: IL-27R alpha/WSX-1/TCCR Antibody [NBP1-76728] - Human spleen tissue with IL27RA antibody at 10 ug/ml.

Applications for IL-27R alpha/WSX-1/TCCR Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

1 ug/ml
Application Notes
An approximately 70 kDa band can be detected in Western Blot.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-27 R alpha/WSX-1/TCCR

Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a . TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.

Long Name

Interleukin-27 Receptor Subunit alpha

Alternate Names

IL-27 R alpha, IL-27Ra, IL27R alpha, IL27RA, TCCR, WSX-1

Gene Symbol

IL27RA

UniProt

NP_004834

Additional IL-27 R alpha/WSX-1/TCCR Products

Product Documents for IL-27R alpha/WSX-1/TCCR Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-27R alpha/WSX-1/TCCR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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