IL-28B/IFN-lambda 3 Antibody (727)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43737

Novus Biologicals, part of Bio-Techne
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NBP2-43737
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 727

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL-28B/IFN-lambda 3 Antibodies »

Product Summary for IL-28B/IFN-lambda 3 Antibody (727)

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human IL-28B/IFN-lambda 3. The exact sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for IL-28B/IFN-lambda 3 Antibody (727)

Western Blot: IL-28B/IFN-lambda 3 Antibody (727) [NBP2-43737]

Western Blot: IL-28B/IFN-lambda 3 Antibody (727) [NBP2-43737]

Western Blot: IL-28B/IFN-lambda 3 Antibody (727) [NBP2-43737] - Analysis of A. 30 ug 293T whole cell lysate/extract B. 30 ug whole cell lysate/extract of GFP-human IL28-transfected 293T cells 10 % SDS-PAGE IL28B antibody [727] dilution: 1:5000.

Applications for IL-28B/IFN-lambda 3 Antibody (727)

Application
Recommended Usage

Western Blot

1:1000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IL-28B/IFN-lambda 3

Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.

Long Name

Interleukin 28B

Alternate Names

IFN-lambda 3

Gene Symbol

IFNL3

Additional IL-28B/IFN-lambda 3 Products

Product Documents for IL-28B/IFN-lambda 3 Antibody (727)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-28B/IFN-lambda 3 Antibody (727)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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