IL-28B/IFN-lambda 3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41236

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all IL-28B/IFN-lambda 3 Antibodies »

Product Summary for IL-28B/IFN-lambda 3 Antibody - BSA Free

Immunogen

Antibody was raised against a 17 amino acid peptide near the center of human IL-28B. The immunogen is located within amino acids 120 - 170 of IL-28B . Amino Acid Squence: IQPQPTAGPRTRGRLH

Specificity

IL-28B antibody is human specific. IL-28B antibody may cross-react with IL-28A and IL-29.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

16 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-28B/IFN-lambda 3 Antibody - BSA Free

Western Blot: IL-28B/IFN-lambda 3 AntibodyBSA Free [NBP2-41236]

Western Blot: IL-28B/IFN-lambda 3 AntibodyBSA Free [NBP2-41236]

Western Blot: IL-28B/IFN-lambda 3 Antibody [NBP2-41236] - Analysis of IL-28B in HeLa cell lysate with IL-28B antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: IL-28B/IFN-lambda 3 Antibody - BSA Free [NBP2-41236]

Immunocytochemistry/ Immunofluorescence: IL-28B/IFN-lambda 3 Antibody - BSA Free [NBP2-41236]

Immunocytochemistry/Immunofluorescence: IL-28B/IFN-lambda 3 Antibody [NBP2-41236] - HeLa cells with IL-28B antibody at 5 ug/mL.

Applications for IL-28B/IFN-lambda 3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-28B/IFN-lambda 3

Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.

Long Name

Interleukin 28B

Alternate Names

IFN-lambda 3

Gene Symbol

IFNL3

Additional IL-28B/IFN-lambda 3 Products

Product Documents for IL-28B/IFN-lambda 3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-28B/IFN-lambda 3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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