IL-28R alpha/IFN-lambda R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84381

Novus Biologicals, part of Bio-Techne
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NBP1-84381
NBP1-84381-25ul
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Block/Neutralize, IF/IHC, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL-28 R alpha/IFN-lambda R1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEAN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-28R alpha/IFN-lambda R1 Antibody

Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381]

Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381]

Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381] - Staining of human small intestine shows membranous/cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381]

Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381]

Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381] - Staining of human cervix, uterine shows moderate membranous/cytoplasmic positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381]

Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381]

Immunohistochemistry-Paraffin: IL-28R alpha/IFN-lambda R1 Antibody [NBP1-84381] - Staining of human duodenum shows membranous/cytoplasmic positivity in glandular cells.
View 1 more images

Applications for IL-28R alpha/IFN-lambda R1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-28 R alpha/IFN-lambda R1

IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain.

Long Name

Interleukin 28 Receptor alpha

Alternate Names

CRF2-12, IFN-lambda R1, IFNLR1, IL-28Ra, IL28R alpha, IL28RA, LICR2

Entrez Gene IDs

163702 (Human)

Gene Symbol

IFNLR1

UniProt

Q8IU57 (Human)

Additional IL-28 R alpha/IFN-lambda R1 Products

Product Documents for IL-28R alpha/IFN-lambda R1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-28R alpha/IFN-lambda R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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