IL-31 Antibody (8-C3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80396

Novus Biologicals, part of Bio-Techne
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NBP2-80396
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Clone # 8-C3

Concentration

2 mg/ml

View all IL-31 Antibodies »

Product Specifications

Immunogen

Recombinant protein within Human IL-31 aa 1-164 / 164. (SwissProt: Q6EBC2 Human)

Localization

Secreted.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Theoretical MW

18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-31 Antibody (8-C3)

Western Blot: IL-31 Antibody (8-C3) [NBP2-80396]

Western Blot: IL-31 Antibody (8-C3) [NBP2-80396]

Western Blot: IL-31 Antibody (8-C3) [NBP2-80396] - Analysis of IL-31 on recombinant protein lysate using anti-IL-31 antibody at 1/500 dilution.
Immunocytochemistry/ Immunofluorescence: IL-31 Antibody (8-C3) [NBP2-80396]

Immunocytochemistry/ Immunofluorescence: IL-31 Antibody (8-C3) [NBP2-80396]

Immunocytochemistry/Immunofluorescence: IL-31 Antibody (8-C3) [NBP2-80396] - Staining IL-31 (green) in MCF-7 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
Immunohistochemistry-Paraffin: IL-31 Antibody (8-C3) [NBP2-80396]

Immunohistochemistry-Paraffin: IL-31 Antibody (8-C3) [NBP2-80396]

Immunohistochemistry-Paraffin: IL-31 Antibody (8-C3) [NBP2-80396] - Analysis in human spleen tissue using IL-31 antibody. Counter stained with hematoxylin.
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Applications for IL-31 Antibody (8-C3)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH7.4), 0.2% BSA, 50% Glycerol

Preservative

0.05% Sodium Azide

Concentration

2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-31

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting ofIL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma(Dillon et al., 2004 (PubMed 15184896)).(supplied by OMIM)

Long Name

Interleukin 31

Alternate Names

IL31

Gene Symbol

IL31

Additional IL-31 Products

Product Documents for IL-31 Antibody (8-C3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-31 Antibody (8-C3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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